1 in 8 men in the USA will be diagnosed with prostate cancer in their lifetime.

Prostate cancer is the most commonly diagnosed cancer in men in the United States. Globally, more than 1.4 million men are diagnosed with prostate cancer each year.

Across the country, there are almost 3.25 million men living with and beyond the disease. Many are dealing with serious side effects from treatment.

IT DOESN’T HAVE TO BE LIKE THIS.
So we’re taking action.

We’ve spent years immersed in prostate cancer research, and in that time, we’ve pushed progress forward 50 years. How? By thinking differently, collaborating globally and investing quickly in what works.

Help us get there.

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“I'd like to imagine my son growing up in a world where prostate cancer can be cured. In a world where the way Dad freely talked about his health and his regular health checks isn’t unique, but the norm.”

Charlotte Connell

This is how we’re going to win the fight.

Our weapons of choice? Innovation and collaboration. We think differently. We back fresh and promising ideas. We unite researchers and experts across the world to chase down breakthroughs in prostate cancer, from early detection through to diagnosis, treatment and support. And we’re always steered by the question: what works for men?
It’s not just about a cure – it’s about quality of life.

The plan of attack

1. Taking action early

Helping men know the signs, symptoms and risk factors for prostate cancer.

2. Bright minds brought together

We’re bringing the best minds from around the world together to collaborate.

3. Tackling biology

Increasing the knowledge of the most lethal prostate cancer tumors, and how to slow or stop its progression.

4. Reducing side effects

No matter where they are in the world, men and their families and carers must have access to services and support.

5. Affordable treatment

We’re influencing governments to provide affordable treatment and to get new treatments into practice faster.

6. Tailored treatments, precision care

Personalized treatment is the new frontier of cancer research. From distinguishing between harmless and lethal cancers, to taking into account genes, lifestyle and environment: it means a better outcome for men.

7. Helping men make tough choices

Men need the right info to understand their diagnosis and make an informed decision when it comes to treatment.

8. Raising the standard

We’re identifying excellence in prostate cancer treatment and care, to reduce the number of men who aren’t getting the best outcome possible.

9. Global initiatives

Our three largest investments in prostate cancer are global projects that will mean better outcomes for men everywhere.

Download our investment strategy

Movember has funded more than 1,320 men’s health projects across more than 20 countries. Here’s a snapshot of our work in prostate cancer.

GLOBAL COLLABORATION

The key to progress? Collaboration. We connect researchers around the world, achieving faster results to reach men sooner. We share our successes and our failures so the scientific community doesn’t lose time to duplicating research.

Global Action Plan

Movember works with leading researchers from around the world to identify key research areas to work together on. Since 2011, Movember has committed $43 million AUD to seven key global research projects in prostate and testicular cancer:
 
 

True North

True North is a global prostate cancer program developed by Movember to help improve outcomes and quality of life for men diagnosed with prostate cancer. With the help of clinicians, researchers, health organisations and user feedback, True North aims to provide information, resources and support to help men navigate the prostate cancer journey.
Visit the True North website
 
 

Clinical quality

Our clinical quality initiatives are transforming prostate cancer healthcare globally by building a better understanding of men’s experiences. By compiling reports from both doctors and patients throughout diagnosis and treatment – and comparing these experiences across regions – we’re improving the quality of prostate cancer care, and reducing treatment variation by continually learning, benchmarking and promoting excellence. These initiatives are active in 18 countries.

The world's first precision medicine drug for treating prostate cancer 

Movember-funded research by Dr Joaquin Mateo contributed to the approval of olaparib in the United States for metastatic, castration-resistant prostate cancer (advanced prostate cancer).  Olaparib works by targeting cancer cell’s ability to repair damage to their DNA. Read on.

Patient Reported Outcome Measure (PROMs)

The Prostate Cancer Patient Reported Outcome Measure (PROMs) is a survey of all men diagnosed with Prostate Cancer at various timepoints in their clinical care. The survey aims to understand more about the experiences of a man with prostate cancer and then make recommendations on how health services can adapt to improve a man’s health and wellbeing as well as influence policy.

Advances in prostate cancer imaging

18F-Fluciclovine is a novel radiotracer for whole-body imaging of prostate cancer tumours using Positron Emission Tomography (PET). Approved in the United States for detection of recurrent prostate cancer in men with elevated PSA levels after previous treatment, it is now marketed by Blue Earth Diagnostics as Axumin®.

Latest breakthroughs in new drugs

Enzalutamide and abiraterone are two androgen receptor-targeted drugs approved in the United States for men whose prostate cancer has spread to other areas of their body. Movember funding for the Prostate Cancer Clinical Trial Consortium supported pivotal clinical research which contributed to the approval of Enzalutamide (Xtandi®) and abiraterone (Zytiga®).

Local impact

In addition to large-scale efforts that span the globe, we’re also making strides for men in the US, in partnership with the Prostate Cancer Foundation (PCF).

Research into targeted radiation therapy

The ORIOLE trial showed that intense doses of radiation targeting tumours that have spread may slow the disease progression in men who have less than a handful of prostate cancer tumours spread outside of the prostate gland (oligometastatic prostate cancer). Outcomes for men treated with targeted radiation therapy (stereotactic ablative radiation) were compared to 'watch and wait' observation. Read on.

A game-changing new blood test

Oncotype DX AR-V7 Nucleus Detect® is a blood test which detects protein found on prostate cancers. Men who carry this protein are likely to be resistant to certain drugs, so being able to identify whether or not a man carries this protein can help to inform the best treatment plan. The test is Medicare reimbursed for men with advanced disease. Read on.

Forward Momentum 

With Black men twice as likely to die from prostate cancer than the general population, Forward Momentum has been created to highlight and address racial disparities in prostate cancer. In partnership with BlackDoctor.org, Evidation Health and Myovant Sciences we’re working to increase diversity in medical research as well as building new digital resources that support the physical and mental health of Black men navigating the prostate cancer journey. Read on.

See all prostate cancer projects

WE’VE MADE EPIC INROADS

But there’s more to be done. Men with prostate cancer still face invasive treatments, serious treatment-related side effects and life or death questions. On top of all that, awareness around early detection has a long way to go. But we’re on it.

Movember is on a mission to change men’s health.
We need your help.

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